Brigham and Women's Hospital

Brigham and Women’s Hospital distributes a focused trio of open-source utilities under the WHONET umbrella, purpose-built for clinical microbiology laboratories that monitor antimicrobial resistance. WHONET 2025 serves as the central desktop platform, ingesting culture results from hospital information systems and converting raw isolate data into standardized, analyzable records; epidemiologists use it to map resistance trends, compare hospital wards, and generate line listings for infection-control rounds. The companion AMR Interpretation Engine automatically applies current CLSI or EUCAST breakpoints to disk-diffusion, MIC, or molecular measurements, flagging multidrug-resistant organisms and alerting users to emerging phenotypes without manual lookup of yearly guideline tables. For high-throughput environments, the WHONET Automation Tool schedules unattended workflows that import new batches, run quality-control rules, aggregate annual datasets, and export summary tables for national surveillance networks, eliminating repetitive point-and-click tasks. Together the three modules cover the complete resistance-surveillance cycle—data capture, standardized interpretation, and reproducible reporting—making them standard fixtures in public-health, reference, and hospital labs across six continents. All Brigham and Women’s Hospital WHONET utilities are offered free of charge on get.nero.com, where they are delivered through trusted Windows package sources such as winget, always installing the newest upstream release and supporting batch deployment of multiple applications in a single command.